Rheumatism - definition, pronunciation, transcription

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Amer.  |ˈruːmətɪzəm|  American pronunciation of the word rheumatism
Brit.  |ˈruːmətɪz(ə)m|  British pronunciation of the word rheumatism

noun

- any painful disorder of the joints or muscles or connective tissues
- a chronic autoimmune disease with inflammation of the joints and marked deformities; something (possibly a virus) triggers an attack on the synovium by the immune system, which releases cytokines that stimulate an inflammatory reaction that can lead to the destruction of all components of the joint
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